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Gamunex (Immune Globulin Intravenous (Human) 10%) Drug Information ...

GAMUNEX may be diluted with 5% dextrose in water (D5/W). Admixtures of GAMUNEX with other drugs and intravenous solutions have not been evaluated. It is recommended that GAMUNEX be administered separately from other drugs or medications which the patient may ... GAMUNEX contains trace amounts of IgA (average 46 micrograms/mL). It is contraindicated in IgA deficient patients with antibodies against IgA and history of hypersensitivity. (See Patient Counseling Information) ...

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Regional Anesthesia Topic of the Week: Obstetric Anesthesia

Dosage per height of patient (cm) Bupivacaine 0.75% in8.25% Dextrose (mL) Bupivacaine 0.5% (isobaric) (mL) 150–160 cm 8 8 160–180 cm 10 10–12.5 >180 cm 12 12.5–15 Onset of action 2–4 min 5–10 min Clinical Pearls ...

Surgical Infectious Disease. Prophylaxis

July 7, 2009 · Posted in GENERAL TOPICS · Comment 

PROPHYLAXIS

17. Should systemic antibiotic prophylaxis be used in elective colon resection?

Show answer
Yes, beyond any statistical shadow of a doubt. At least two dozen clinical trials have been carried out using placebo controls against a variety of antibiotics, principally those active against at least the anaerobic-predominant flora, and nearly all have shown a reduction in infectious complications in the antibiotic group. Never again should this point need repeating, and no patient should be placed at risk when systemic antibiotic prophylaxis has been established as the standard of care. No new clinical trials against placebo in this group of patients with known risk can be performed ethically given the confirmed risk reduction.
Other risk groups (e.g., cesarean section after membrane rupture) besides patients undergoing colon resection have been standardized by trials in large patient populations and have shown similar risk reduction. The benefit of prophylaxis has been demonstrated. In other groups of patients that cannot be standardized because of unusual contamination factors or unique factors of host resistance impairment, guidelines for rational prophylaxis should follow similar principles.
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What Is Pulmonary Insufficiency?

July 6, 2009 · Posted in GENERAL TOPICS · Comment 

5 WHAT IS PULMONARY INSUFFICIENCY?
Alden H. Harken M.D.

1. What is pulmonary insufficiency?

how answer
The alveolar-capillary surface of the lung is the size of a singles tennis court. The purpose of the lung is to match alveolar ventilation (Va) to blood flow (Q). Mismatching leads to pulmonary insufficiency.

2. How is Va/Q mismatching characterized?

Show answer
Shunt: decreased ventilation relative to regional blood flow; pulmonary arterial (unoxygenated) blood “shunts” by hypoventilated alveoli
Dead space: decreased pulmonary regional blood flow relative to ventilation
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Basic Care Of Hand Injuries

July 8, 2009 · Posted in TRAUMA · Comment 

34 BASIC CARE OF HAND INJURIES
Michael J.V. Gordon M.D., Lawrence L. Ketch M.D.

1. What are the goals of hand repair?

Show answer
Functional considerations override cosmesis in the treatment of hand trauma. There are no minor hand injuries. Initial diagnosis and management determine the final result; expert secondary repair cannot overcome primary errors in diagnosis or decision making.
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Surgical Infectious Disease. Extra Credit Questions

July 7, 2009 · Posted in GENERAL TOPICS · Comment 

EXTRA-CREDIT QUESTIONS

25. Should all patients undergoing elective laparotomy receive prophylactic antibiotic coverage?

Show answer
No. Doing so would contribute to driving up the cost of antibiotics and their complication rate and devaluing formerly good drugs by rendering them useless against common flora against which they were once highly potent. Operating room nurses have always classified the kind of operation by its status with respect to microbial exposure: clean, contaminated, or septic. These categories are approximation of the microbial risk exposure, and if additionally are superimposed categories of patient resistance (higher risk associated with aging, obesity or other malnutrition, concomitant drugs, or viral or mycobacterial or neoplastic disease immune compromise), these same strata are called class I, II, and III.

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Penetrating Neck Trauma

July 7, 2009 · Posted in TRAUMA · Comment 

20 PENETRATING NECK TRAUMA
Clay Cothren M.D., Ernest E. Moore M.D.

1. Why are penetrating neck wounds unique?

Show answer
Although comprising only a small percentage of body surface area, the neck contains a heavy concentration of vital structures.
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Traumatic Brain Injury

July 7, 2009 · Posted in TRAUMA · Comment 

18 TRAUMATIC BRAIN INJURY
J. Paul Elliott M.D., Sanjay Misra M.D.

1. Is traumatic brain injury (TBI) a common problem?

Show answer
Yes. In the United States, 1 in 12 deaths is due to injury. One third of traumatic deaths are associated with TBI. Of deaths resulting from motor vehicle accidents, 60% are due to brain injury. Even more common is minor TBI, which accounts for 75% of admissions for head trauma.

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Hodgkin Disease & Malignant Lymphomas

July 9, 2009 · Posted in WHAT IS CANCER · Comment 

66 HODGKIN’S DISEASE AND MALIGNANT LYMPHOMAS
Christina A. Finlayson M.D.

1. What is the differential diagnosis of lymphadenopathy?

Show answer
The significance of cervical, axillary, or inguinal lymphadenopathy depends on the characteristics of the lymph nodes and associated symptoms. Infection, autoimmune disease, and malignancy are all included in the differential diagnosis.

2. What historical information helps to direct the diagnostic investigation of lymphadenopathy?

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Queries 5

September 21, 2009 · Posted in Uncategorized · Comments Off 

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Ethics In The Surgical Intensive Care Unit

July 14, 2009 · Posted in HEALTH CARE · Comment 

102 ETHICS IN THE SURGICAL INTENSIVE CARE UNIT
Ricardo J. Gonzalez M.D.

1. What are the four principles of medical ethics?

1. Beneficence describes the active role of doing good by intervention.
2. Nonmaleficence is equivalent to saying, “First do no harm.”
3. Autonomy accounts for informed consent, competence, and the patient’s right to refuse treatment and to know what’s going on.
4. Justice means that all patients should receive fair and equal care but that one patient’s care should not squander limited resources for others.
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Urodynamics & Voiding Dysfunction

July 14, 2009 · Posted in UROLOGY · 1 Comment 

98 URODYNAMICS AND VOIDING DYSFUNCTION
Firouz Daneshgari M.D.

1. What is urodynamics?

Show answer
Urodynamic studies assess the functional aspects of the storage and emptying ability of the lower urinary tract (LUT). The principles of urodynamic studies originated from hydrodynamics. The components of urodynamic studies are cystometrogram, leak point pressures, urethral profile pressures, pressure-flow studies, uroflowmetry, and electromyography. These studies have evolved into videourodynamics with the addition of fluoroscopy (i.e., video).
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Urinary Calculus Disease. Bonus Questions

July 14, 2009 · Posted in UROLOGY · 1 Comment 

BONUS QUESTIONS

11. Is there any type of stone that cannot be seen on helical CT scan?

Show answer
Patients taking indinavir sulfate (Crixivan) for HIV infection can form stones from the crystals of the medication; these stones are not seen on CT scan.
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Renal Cell Carcinoma. Bonus Question

July 14, 2009 · Posted in UROLOGY · Comment 

BONUS QUESTION
9. What is Stauffer’s syndrome? Show answer
It is diagnosed with elevated liver function tests (LFTs) in the presence of renal cell carcinoma that normalize after nephrectomy and tumor removal. It is thought to be a type of paraneoplastic syndrome.
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Renal Cell Carcinoma

July 14, 2009 · Posted in UROLOGY · Comment 

95 RENAL CELL CARCINOMA
Brett B. Abernathy M.D.

1. How common is renal cell carcinoma?

Show answer
In the United States, 30,000 new cases of renal cell carcinoma are predicted for 2004 and 2005, about 3% of all adult malignancies.
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Urinary Calculus Disease

July 14, 2009 · Posted in UROLOGY · Comment 

94 URINARY CALCULUS DISEASE
Bretat B. Abernathy M.D.

1. What are the most common types of urinary stones found in North America?

Show answer

* Calcium stones (calcium oxalate, calcium phosphate, or mixed calcium stones): 70%.
* Struvite or magnesium ammonium phosphate stones, often associated with infection: 20%.
* Uric acid stones (radiolucent): 5%
* Cystine stones, often with a genetic association: 5% Read more

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Surgical Approach To Infertility

July 14, 2009 · Posted in UROLOGY · Comment 

93 THE SURGICAL APPROACH TO INFERTILITY
Randall B. Meacham M.D., Alex J. Vanni


1. How common a problem is infertility?

Show answer
Infertility is the inability to establish a pregnancy during 1 year of well-timed intercourse. This affects 15% of all couples in the United States. In 50% of such couples, the woman is responsible; in 30% of couples, a male factor prevents pregnancy; and in 20% of couples, it is a combination of both.

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    Author / s: Harken Alden H., Abernathy Charles, Moore Ernest Eugene
    Year: 2004
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    Publishers: Elsevier Mosby; 5th Bk & Acc edition
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